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Biochemistry
第6次开课
开课时间: 2023年03月06日 ~ 2023年06月30日
学时安排: 3小时每周
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课程评价(211)
spContent=Why are we energetic after a meal? Why are we motivated even when we're hungry? How can the body help us through the difficulties? How do various drugs treat diseases and where are their targets? Biochemistry is to explore and study the phenomenon of life at the molecular level. Please follow us to explore the mystery of life! Let's enjoy the beauty of biological science and the charm of scientific research!
Why are we energetic after a meal? Why are we motivated even when we're hungry? How can the body help us through the difficulties? How do various drugs treat diseases and where are their targets? Biochemistry is to explore and study the phenomenon of life at the molecular level. Please follow us to explore the mystery of life! Let's enjoy the beauty of biological science and the charm of scientific research!
—— 课程团队
课程概述

Biochemistry is the science concerned with the chemical basis of life, that is, with the chemical constituents of living cells and with the reactions and processes they undergo. By this definition, metabolism is one of the most important part in biochemistry. The teaching purpose of Metabolism of Biochemistry is to make the students understand at the molecular level of all chemical processes associated with living cells, clinical diseases and biological drugs. According to the necessity of medicine, the teaching program will focus on the basic concept and knowledge of the metabolism pathways of sugar, lipids and proteins.

This course focus on the biochemical metabolism, which is a highly coordinated cellular activity in the body. The numerous metabolic pathways cooperate to (1) obtain chemical energy; (2) convert nutrient molecules into the cell’s own characteristic molecules; (3) synthesize and degrade biomolecules required for specialized cellular functions. 





授课目标


    

课程大纲

Chapter1 Introduction to Metabolism

1.1 Introduction to Metabolism

1.2 Regulation of enzyme activity

quiz1

Chapter2 Carbohydrate Metabolism

2.1 Introduction of sugar metabolism

2.2 Preparatory stage of Glycolysis

2.3 Payoff stage of Glycolysis

2.4 Regulation of Glycolysis

2.5 Lactate fermentation

2.6 PDH complex

2.7 Citric acid cycle

2.8 Regulation of citric acid cycle

2.9 Pentose phosphate pathway

2.10 Glycogen biosynthesis

2.11 Glycogen breakdown

2.12 Regulation of glycogen synthase

2.13 Regulation of glycogen phosphorylase

2.14 Gluconeogenesis

2.15 Cori cycle

quiz2

Homework

Chapter3 Biology Oxidation

3.1 Oxidative phosphorylation

3.2 Respiratory chain

3.3 Chemiosmotic hypothesis

3.4 ATP synthase

3.5 Regulation of oxidative phosphorylation

3.6 Shuttle systems

quiz3

Chapter4 Lipids Metabolism

4.1 Lipolysis

4.2 beta-oxidation

4.3 Fatty acid biosynthesis

4.4 Fatty acid biosynthesis and breakdown

4.5 Sugar and Fat

4.6 Ketone bodies

4.7 The metabolism of phospholipids

4.8 Cholesterol biosynthesis

4.9 Derivatives of Cholesterol

4.10 Metabolism of plasma TAG

4.11 Metabolism of plasma cholesterol

Homework

quiz4

Chapter5 Metabolism of Amino Acids

5.1 Introduction of amino acid catabolism

5.2 Protein degradation

5.3 Deamination

5.4 Disposal of Ammonia

5.5 Urea cycle

5.6 Metabolism of Amino Acid carbon skeletons

5.7 Metabolism of one carbon

quiz5

Homework

展开全部
预备知识

Chemistry of Protein 

参考资料

1.Lehninger Principles of Biochemistry 7th edition. 

2.Biochemistry.W.H.Freeman.8th(2015)

China Medical University
1 位授课老师
Xuesong LI

Xuesong LI

讲师

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