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College Chemistry(II)
第1次开课
开课时间: 2021年03月16日 ~ 2021年06月28日
学时安排: 3
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spContent=In the ocean of science, chemistry is known as the “central science” because it is the bridge between many disciplines and involves all aspects of human life. The “College Chemistry” course is divided into two parts, led by Wang Yifan and Wang Weihong respectively.
In the ocean of science, chemistry is known as the “central science” because it is the bridge between many disciplines and involves all aspects of human life. The “College Chemistry” course is divided into two parts, led by Wang Yifan and Wang Weihong respectively.
—— 课程团队
课程概述

Chemistry provides the foundation for humanity's initial march towards civilization! It is also the driving force for the sustainable development of modern society!

Our “College Chemistry” teaching emphasizes the scientificity and the systematization, and strives to be simple and easy to understand.

The English instructors of College Chemistry(I) international edition are Liu Shaoqian, Yi Xiaoyi, Yan Jun, Xiang Juan, He Zhen,He Piao, Liu Chao, etc.

The English instructors of College Chemistry(Ⅱ) international edition are Peng Hongjian, Liang Wenjie, Chen Guohui, Yu Jingang, Li Xiaoru, Shi Shuyun, Xiang Haoyue, Yu Guipeng, Lan Minhuan, Jiang Lihui, Sun Xiaoyi, Chen Yin, Hu Yunbin, etc.

The excellent online open course of “College Chemistry” of Central South University has 80 class hours in total, divided into the first and second parts. Among them, “College Chemistry (I)” has 40 class hours, including the basic knowledge of inorganic chemistry, analytical chemistry and physical chemistry; “College Chemistry (II)” has 40 class hours, including the basic content of organic chemistry. This course is not only a public basic course for non-chemistry and non-chemical engineering majors, but also an important way for college students and social learners, including liberal arts students, to strengthen quality education and inspire innovative thinking. At the same time, the course is also an independent learning platform for students in the majors of biomedicine, mineral materials, geological engineering, safety engineering and other majors of Central South University to carry out the teaching reform of “flip classroom” and “Open Boutique Demonstration Classroom”.

The medical chemistry education of Central South University originated in the period of Xiangya Medical University in 1916, and the general chemistry education began in 1952 when the Mining and Metallurgy of Central South University was founded. Since the merger of the university in 2000, the course has inherited the centuries-old teaching tradition of Xiangya. Through the integration of science, engineering, and medicine, it has continuously achieved new achievements in teaching reform and curriculum construction. Among the 19 members of the teaching team, there are 7 professors, 13 associate professors, 2 lecturers, including 11 doctors; 1 provincial university teaching dedication award, 1 Baosteel excellent teacher award, 1 school-level teacher, 5 provincial university young teachers teaching competition first prize, 1 provincial young teachers courseware competition first prize, 1 youth thousand talents program of the central organization department; Most of them are leaders, organizers, speakers or team members in the four “national quality resource sharing courses” including inorganic chemistry and organic chemistry.

        “College Chemistry (I)” has a total of 18 lectures and 11 teachers. The content includes the following four modules: “(1) Principles of Inorganic Chemistry, (2) Basis of Material Structure, (3) Analytical Chemistry, (4) Element Chemistry and Materials”. Undergraduate students majoring in biomedical carry out the 56-hour course “Basic Chemistry” in the teaching reform of “flipped classroom” and “Open Boutique Demonstration Classroom”. Lectures 1-15 can be selected for learning, which involve the knowledge of three modules of “(1) Principles of Inorganic Chemistry, (2) Fundamentals of Material Structure, (3) Analytical Chemistry”; Undergraduates majoring in geological engineering and safety engineering specialize in the 56-hour “General Chemistry” course of teaching reform of “Mixed Teaching Based on MOOCs” and “Open Boutique Demonstration Classroom”. Lecture 1-4, 6-13 and 16-18 can be selected for learning, involving the knowledge of three modules “(1) Principles of Inorganic Chemistry, (2) Fundamentals of Material Structure (4) Element Chemistry and Materials”.


授课目标

Let students master the basic principles and basic knowledge of chemistry.

To introduce students to the application of chemistry in medical and engineering practice.

Inspire students' sense of innovation.

To cultivate students' ability of analyzing and solving problems, to enhance their ability of applying modern information technology and self-learning, and to lay a certain chemical foundation for their subsequent courses and career.


课程大纲
Chapter 1 Introduction
1.1 Research object of organic chemistry
1.2 Structural characteristics of organic compounds
1.2.1 σ bond and π bond
1.2.2 Three kinds of hybrid orbitals for carbon
1.2.3 Polarity and polarization of covalent bonds
1.2.4 Covalent bond breaking and organic reaction type
1.3 Concept of acid and base in organic reaction
Chapter 2 Nomenclature of Organic Compounds
2.1.1 Adjectives which are used to describe the isomerism of carbon chain
2.1.2 Structure and name of common groups
2.2.1 The Basic Method of IUPAC names
2.2.2 Group sequence rules
2.3.1 Nomenclature of open chain alkanes, alkenes and alkynes
2.3.2 Nomenclature of alicyclic hydrocarbons and aromatic hydrocarbons
2.4.1 Nomenclature of halohydrocarbons
2.4.2 Nomenclature of alcohol, phenol and ether
2.4.3 Nomenclature of aldehydes and ketones
2.4.4 Nomenclature of carboxylic acids and their substituted carboxylic acids
2.4.5 Nomenclature of carboxylic acid derivatives
Chapter 3 Basis of Stereochemitry
3.1.1 Conformation of alkanes
3.1.2 Conformations of cycloalkanes
3.2 Cis-trans isomerism
3.3.1 Plane polarized light and optical activity
3.3.3 Representation of enantiomers
3.3.4 Nomenclature of Enantiomers
3.3.5 Enantiomerism of compounds containing chiral carbons
3.3.6 Enantiomerism for alicyclic compounds
3.3.7 Enantiomers without Chiral Carbon Atoms
3.3.8 Methods for obtaining single enantiomer
3.3.2 Chirality and Symmetry
Chapter 4 Alkanes and Cycloalkanes
4.1 Structure of Alkanes
4.2.1 Mechanism of halogenation and free radical substitutionof methane
4.2.2 Orientation of halogenations and stability of free radical
4.2.3 Reactivity and selectivity
4.3.1 Chemical properties of cycloalkanes
4.3.2 The structure and stability of cycloalkanes
Chapter 5 Alkenes, Alkynes and Dienes
5.1 Structure and reactivities of alkenes and alkynes
5.2.1 Catalytic hydrogenation
5.2.2 Electrophilic addition reaction
5.2.3 Mechanism of electrophilic addition reaction
5.2.4 Inductive effect and the mechanism for Markovnikov’s rule
5.2.5 Free radical addition of alkenes
5.2.6 Oxidation reaction
5.2.7 Halogenation of α-hydrogen of alkenes and reactivity of terminal hydrogen of Alkynes
5.3 Introduction of resonance theory
5.4.1 Structural characteristics of conjugated dienes
5.4.2 Conjugate system and conjugate effect
5.4.3 Characteristic reactions of conjugated dienes
Chapter 6 Aromatic Hydrocarbons
6.1 Structure of benzene
6.2 Chemistry properties of benzene
6.2.1 Electrophilic substitution of benzene
6.2.2 Halogenation of benzene
6.2.3 Nitration of benzene
6.2.4 Sulfonation of benzene
6.2.5 Friedel-Crafts reactions of benzene
6.2.6 Effect of substituents on orientation (two classes of directors)
6.2.7 Effect of ortho-para directors
6.2.8 Effect of meta directors on orientation
6.2.9 Effect on orientation of disubstituted benzene
6.2.10 Application of orientating rule
6.2.11 Reactions on the side chain of alkyl benzene
6.3 structure and electrophilic substitution reaction of naphthalene
6.4 electrophilic substitution reaction and orientation of substituted naphthalene
6.5 Recognizing the aromaticity of other cyclic conjugated polyenes
Chapter 7 Halohydrocarbons
7.1 Classification, structure and reactivity analysis of halohydrocarbons
7.2 Nucleophilic substitution of RX
7.3 The mechanism of bimolecular nucleophilic substitution (SN2)
7.4 The mechanism of unimolecularnucleophilic substitution (SN1)
7.5 Factors affecting nucleophilic substitution reaction
7.6 Elimination reaction and mechanism of RX
7.7 Competition between Elimination and substitution reactions
7.8 Substitution reaction of haloalkenes and haloarenes
7.9 Reaction of halohydrocarbon with metal
Chapter 8 Alcohols and Phenols
8.1.1 Classification, structure and physical properties of alcohols
8.1.2 Chemical properties of alcohols (1) Weak acidity, halogenation reaction
8.1.3 Chemical properties of alcohols (2) dehydration reaction
8.1.4 Chemical properties of alcohols (3) Esterification, oxidation and characteristic reactions of vicinal diol
8.2 Phenols
Chapter 9 Ethers and Epoxides
9.1 Classification and structures of ethers, functions of crown ethers
9.2 The chemical properties of ethers
9.3 Epoxides
Chapter 10 Spectrometric Identification of Organic Compounds
10.1 Introduction of Spectrometric Identification of Organic Compounds
10.2.1 Basic theory of IR spectrum
10.2.2 Characteristic absorption frequency and influence factor of IR spectrum
10.2.3 Interpretation of IR spectrum
10.3.1 The basic principle of 1H NMR spectrum
10.3.2 Shielding effect and chemical shift
10.3.3 Factors affecting chemical shifts and characteristic 1H chemical shifts
10.3.4 Spin coupling and proton numbers
10.3.5 Interpretation of 1H NMR spectrum
Chapter 11 Aldehydes and ketones
11.1 Structure and spectral properties of aldehydes and ketones
11.2 Nucleophilic addition reactions
11.2.1 Mechanism and reactivity of nucleophilic addition reaction
11.2.2 Addition aldehydes and ketones with nucleophiles containing carbon
11.2.3 Addition of aldehydes and ketones with reagents containing oxygen
11.2.4 Addition of aldehydes and ketones with sodium bisulfite
11.2.5 Addition of aldehydes and ketones with nucleophiles containing nitrogen
11.3 Reactions of α-H of aldehyde or ketone
11.3.1 Halogenation of α-H of aldehyde or ketone
11.3.2 Aldol condensation of aldehydes and ketones
11.4 Oxidations and reductions of aldehydes and ketones
11.4.1 Oxidations of aldehydes and ketones
11.4.2 Cannizzaro reaction
11.4.3 Reduction of aldehydes and ketones
Chapter 12 Carboxylic Acids
12.1 Carboxylic Acids
12.1.1 Structure of Carboxylic Acids
12.1.2 Physical Properties and Spectral Properties of Carboxylic Acids
12.1.3 Chemical Properties of Carboxylic Acids
12.1.4 Important Carboxylic Acids in Medicine
12.2. Substitutional Acids
12.2.1 Chemical Properties of Hydroxy Acids
12.2.2 Chemical Properties of Keto Acids
12.2.3 In Vivo Chemical Processes of Alcohol Acids and Keto Acids
12.2.4 Important Hydroxy Acids and Keto Acids in Medicine
Chapter 13 Derivatives of Carboxylic Acids
13.1 Structure of Derivatives of Carboxylic Acids
13.2. Physical Properties and Spectral Properties of Derivatives of Carboxylic Acids
13.3 Chemical Properties of Derivatives of Carboxylic Acid
13.3.1Nucleophilic substitution Reactions
13.3.2 Claisen Condensation of Ester
13.3.3 Keto-enol Tautomerization
13.3.4 Reduction Reactions
13.3.5 Chemical Properties of Amides
13.3.6 Chemical Properties of Derivatives of Carbonic Acid
Chapter 14 Amines
14.1 Classification and nomenclature of amines
14.2 Structure and physical properties of amines
14.3 Alkalinity and salt formation of amines
14.4 Acylation and sulfonation
14.5 Reaction of amines with nitrous acid
14.6 Structure and reaction of diazonium salt
Chapter 15 Heterocyclic Compounds
15.1 Definition, Classification and Nomenclature of Heterocyclic Compounds
15.2.1 Structural characteristics of five-membered heterocyclic compounds
15.2.2 Chemical properties of five-membered heterocyclic compounds
15.2.3 Some representative five-membered heterocyclic compounds
15.3.1 The structure of six-membered heterocyclic compounds
15.3.2 The chemical properties of pyridine
15.3.3 The derivatives of pyridine and pyrimidine
15.4 The fused heterocyclic compounds
Chapter 16 Lipids
16.1 Oils and fats
16.2 Phospholipids
16.3 Terpenes
16.4 Steroids
Chapter 17 Saccharides
17.1 The concept and classification of saccharides
17.2.1 Open chain structure and configuration of monosaccharides
17.2.2 Ring structure of monosaccharide
17.2.3 chemical properties of monosaccharide (I):epimerization, oxidation, reduction and osazone formation
17.2.4 Chemical properties of monosaccharide (II): glycosides, esterification and coloration
17.3 Structure and properties of oligosaccharides
17.4 Structure and properties of Polysaccharides
Chapter 18 Amino Acids, Peptides and Proteins
18.1.1 Amino Acids
18.1.2 Chemical properties of amino acids (I)
18.1.3 Chemical properties of amino acids (II)
18.2 Peptides and proteins
展开全部
预备知识

High school chemistryHigher mathematics;Basic chemistry


参考资料

Organic chemistry (2nd Edition), chemical industry press, editor-in-chief  Wang Weihong, and Luo Yiming, deputy editor-in-chief Peng Hongjian and Wang Weiling, 2020


Central South University
3 位授课老师
Yifan WANG

Yifan WANG

教授

王微宏

王微宏

教授

王微宏

王微宏

教授

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